Fox McCloud

April 24th, 2017 at 2:50 PM ^

Urinalysis check for various drugs are considered dilute when the creatinine (yes creatinine not creatine) levels are below 20 mg/dL. for an average person it would be pretty difficult to achieve this. You would have to drink between 2-4 liters within an hour or 2 of giving the sample. Dilution is the most popular method used to pass drug tests. It pushes out the date for the collection of a testable specimen thus allowing more time for drugs to leave ones system. Dilutions do not prove guilt, but it is what a lot of guilty people do. Peopers dilute is not a cause for concern but definitely noteworthy. Personally he strikes me as too smart of a player to declare early for the draft just so he can fail a drug test and watch his stock drop. Everyone that fails a drug test knows that they will/might fail before they get the results back.

Qmatic

April 24th, 2017 at 2:29 PM ^

Happened to me when I drug tested for a job in the past. I was pounding fluids because I was coming off a virus and my urine was too clear. I had to take a second test the following day and made sure not to drink as much H2O.

mgoDAB

April 24th, 2017 at 2:34 PM ^

Jabrill was on campus over the weekend, and my buddies and I ran into him. We struck up a conversation, and he mentioned how his head has been in the right place all year and he wasn't about to do anything stupid before next week. Probably said so because we had been day drinking and obviously pretty messed up at that point. He was a very genuine and fun guy to talk to. /end of cool story bro

xtramelanin

April 24th, 2017 at 2:41 PM ^

can still look 'behind' the test to see if he was postive for other banned substances, just not enough to meet the minimum threshhold requirements to be a 'postiive' test.   e.g, 50 ng of THC might get you a postive out of one lab.  you won't show postiive if you are less than that, but maybe the presence of THC (or other banned substance) could nevertheless be seen.  

interpretation guidelines here:

Creatinine: In general, creatinine is a metabolic byproduct of muscle metabolism which normally appears in urine in relatively constant quantities over each 24 hour period. Therefore, urine creatinine can be used both as a marker to specifically identify a specimen as urine, and as an indicator of urine water content (dilution). "Normal" random urine specimens will generally have urine creatinine levels of greater than 20 mg/dL, while specimens with creatinine levels between 10 and 20 mg/dL may be due to increased liquid consumption, dietary habits, or liquid ingestion preferences. Urine specimens with creatinine levels between 2 and 10 mg/dL are usually a result of ingestion of large volumes of water (or other liquid), termed short term water loading. This is a very common practice when attempting to dilute a urine so that any drugs in the urine will be diluted below analytical testing cutoff levels. Urine creatinine levels below 2.0 mg/dL indicate the specimen is not consistent with human urine.

Urine specimens become dilute as a result of the short term consumption of large amounts of a liquid due to an unknown stimulus such as a response to heat or exercise, herbal flushes, prescription diuretics, intentional dilution, or pathological situations such as diabetes insipidus. The dilution effect from consuming increased volumes of liquid can last from 2 - 5 hours. Therefore, the increased consumption of liquid would have to take place between 2 - 5 hours prior to the collection of the urine specimens.

An important factor to consider when interpreting dilute urine samples is that drug use can never be assumed unless specifically detected, and confirmed in a urine sample. Certainly, a dilute sample can produce false negative results, as drugs in the urine at concentrations near the testing cutoff may be diluted below the testing cutoff level, however, due to the reasons stated above it can be difficult to establish the reason or intent for the sample(s) being dilute. For these reasons, urine creatinine is reported in conjunction with testing for drugs of abuse, as an indicator of specimen validity only, as urine specimens with a creatinine level below 20 mg/dL may have an increased likelihood of producing a false negative drug testing result.

 

BursleyBaitsBus

April 24th, 2017 at 4:50 PM ^

It seems weird because creatinine levels are very sensitive for assessing proper renal function. 

Just changing a plasma creatinine level from 1 to 2 mg/dL means that you lost half of your renal function aka 1 kidney. 

I also would venture to guess that having a simple number like 1 would make mg/dL a more desirable metric for measuring creatinine as well. 

Fox McCloud

April 24th, 2017 at 3:05 PM ^

Great post but as someone who works regularly with drug testing I will say the State of Michigan's Drug lab will detect any level of thc. The lowest I've personally seen is 10. Most drug screening equipment will not detect below 20 or so but actual drug testing with a non diluted sample will reveal any trace amounts.

xtramelanin

April 24th, 2017 at 3:30 PM ^

that, but if you look into the metrology and the actual senstivity of the equipment, they are just spinning a web of b.s.   can they detect some?  of course.  can they detect down to, say, 1 ng/l?  no way, that is just noise on a GCMS.   

Mgotri

April 24th, 2017 at 4:00 PM ^

do you have any data to support your claim? I use GC/MS daily to detect and quantify in the range of 1 ppb. While I haven't looked at THC specifically, some analytes give stronger responses than other and there are techniques you can use to better resolve the peaks from the noise. 

Here's a link to an abstract (from 2006) where they report detecting at 1ppb with a signal to noise ratio (S/N) of 50. Typically the limit of detection is determined from the S/N of 3 while the limit of quatification has an S/N of 10. 

Trublu62

April 24th, 2017 at 4:38 PM ^

I think he meant methodology, lol, but in my toxicology lab we do screens and confirmations on THC and its metobolites in urine and saliva. Most routine analyzers use a cutoff of 20 ng/mL (ppm) for THC. We use LC/MS/MS for the confirmations and have a LLOQ  of 10ng/mL.  That's the lowest value we report but can certainly see peaks below 10 they just aren't reportable.

xtramelanin

April 24th, 2017 at 6:57 PM ^

of measurement.  link here: https://en.wikipedia.org/wiki/Metrology

i'll spare you the 'lol' comment and some others.  

best local expert is dr. andreas stolz.  link to his CV is here: https://people.nscl.msu.edu/~stolz/Stolz_CV.pdf

he runs the national superconducting cyclotron.   there are many studies that back this up, and most knowledgeable forensic scientists will admit/know of this.  it is sometimes called an 'uncertainty budget', but i think that is slightly off. i have some transcripts of my cross, too, but not at desk to link them.  

anyway, enjoy. 

Jimmyisgod

April 24th, 2017 at 2:46 PM ^

Bummer.  It lowers his stock because he's now in the Drug Program and faces stricter testing and increased punishment.  And he has an agent with people around to advise him, they should have known better.

ArrogantAsshole

April 24th, 2017 at 2:47 PM ^

How does this news just come out now, days before the Draft?  The Combine was nearly two months ago, I very much doubt it takes that long to test the sample.  Are NFL personnel privy to the results beforehand?  The failed test is not good, but it seems the timing of the news hurts Jabrill just as much...

redjugador24

April 24th, 2017 at 3:03 PM ^

http://www.wvrestore.org/assets/Avoiding_a_Dilute_Urine98112.pdf

The problem with assuming that dilute urine is always due to attempted cheating is that many individuals drink large amounts of water for health reasons or simply to “be prepared” to provide a urine sample. 

When did MGoBlog become the venue for the hottest of hot takes of which we clearly know nothing? C'mon guys you're better than that!  This is not just me being a homer, I deal with this in the real world on a daily basis.  A diluted sample does NOT necessarily mean anything was tampered with or there was any intentional wrongdoing.  Sure, it could.  But it's also fairly common for people to test dilute when they're just trying to stay hydrated too.  Unfortunately, employers (the NFL) tend to treat dilute samples the same as positive tests to discourage intentionally diluting samples, which is honestly just wrong.  That said this won't affect where he gets drafted because teams won't care - he did NOT test positive, he tested "dilute."  Yes, there's a huge difference.

What his agent said (who is clearly biased towards his client, sure) is perfect and cannot be factually refuted.  "Dilute" samples measure low in specific gravity and/or creatinine, both of which can result from drinking lots of water just before the test.  So.....where is exactly did Jabrill do something wrong?  

Fezzik

April 24th, 2017 at 3:05 PM ^

"Dilute specimen" is not something you can test positive for. It's not a drug. It means the sample was too diluted to give an accurate positive or negative result for the specific drugs being tested for.

NRK

April 24th, 2017 at 3:55 PM ^

Well, kind of...

The NFL uses a common method called "limits of detection" testing, and there are LOD Positive and LOD Negative. Either way you enter Stage 1 of the NFL Substance Abuse program, but for a LOD Negative result you go in under Behavior (providing a diluted sample) and for LOD Positive you go in under a Positive test. They impact you being evaluated, moving onto Stage 2, etc.

 

Full NFL Substance Abuse Policy Link

LV Sports Bettor

April 24th, 2017 at 3:11 PM ^

and he didn't know it........HAHA. How long until someone uses this excuse in the future esp with all the states now legalizing weed. That's be my excuse, must have had a brownie on accident, etc

charblue.

April 24th, 2017 at 3:12 PM ^

generally recommended for employers who are drug testing potential employees whose urine samples come back with a creattine level that rises above two standards that deem it dilute, a false negative, or one that might suggest masking for certain drugs that cannot be detected. The generally accepted method of correcting for this is to perform another test and have it done as soon as possible with little notice.

We know that Jabrill's record at Michigan was that of an ideal player who was a tremendous performer who didn't enhance that performance or deter from it by use of drugs, even a hint of it recreationally. Of course, we don't know that for certain but his character was never shaded by even a hint of that suggestion in the press during his time in school.

I would tend to believe the account his camp offered in explanation for the dilute sample and would expect that future testing would bear out the aberrational result.

uncle leo

April 24th, 2017 at 4:07 PM ^

Jabrill participated in anything extra-curricular as a wildly successful D1 athlete who could probably get whatever he wanted at any college party on campus? Hate to break it to you boss, but most of these guys party, and it's not one of those lame middle school water balloon parties.

I don't really know what you are trying to say by "his character was never shaded by a hint of that suggestion in the press." Do you expect the press to go out to every party and post that an athlete has drank or smoked pot?? 

Jimmyisgod

April 24th, 2017 at 3:13 PM ^

Here's the thing, when he hired an agent he stopped being an amateur.  His agent has people to help Jabrill with this type of stuff.  He's not just flying to the combine alone and eating and drinking what he thought he needed, he would have had a trainer with him thinking about stuff like dilluted samples.

He'll be 2nd round pick now, might have already been one.  Not a huge deal but he will be under stricter tests now and he'll be suspended if he has another failed test.

bronxblue

April 24th, 2017 at 3:53 PM ^

I despise when shit like this happens.  The NFL doesn't have any other proof but this test, probably didn't do any follow-ups, and will just let this hang out there without any additional evidence because the same people who couldn't disprove footballs sometimes lose air just assume diluted urine is a sign of cheating.  

Esterhaus

April 24th, 2017 at 4:24 PM ^

 

Is Jabrill's dilithium dealer? I guess that makes sense. Stigmatizing for dihydrogen oxide use however makes far less sense if not promptly followed up with blood and hair tests IMHO. Not an apologist, but not convinced either. And my avatar played a cop on TV and probably slept at a Holiday Inn to boot.

mgobleu

April 24th, 2017 at 4:34 PM ^

Well Jabrill, it's a shit mess but come on back to the ones who really love ya. Use that eligibility you've got left, win the Heisman and you'll go #1 next year, eh sport? Whaddya say???