OT: Potentially Good news for a therapeutic

Submitted by WesternWolverine96 on April 16th, 2020 at 5:49 PM

This could help. We need some good news.  I want to believe.

 

https://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/?mod=article_inline

 

"A Chicago hospital treating severe Covid-19 patients with Gilead Sciences’ antiviral medicine remdesivir in a closely watched clinical trial is seeing rapid recoveries in fever and respiratory symptoms, with nearly all patients discharged in less than a week, STAT has learned."

 

awill76

April 17th, 2020 at 1:37 AM ^

I think that's incorrect.  That report in the New England Journal of Medicine tracked "53 people in the U.S., Europe,  and Canada who needed respiratory support..."  https://www.bloomberg.com/news/articles/2020-04-10/two-thirds-of-severe-covid-19-improved-on-gilead-s-remdesivir 

Whereas this latest report is from the University of Chicago where 125 patients infected with COVID-19 were treated with Remdesivir and results studied:  https://www.statnews.com/2020/04/16/early-peek-at-data-on-gilead-coronavirus-drug-suggests-patients-are-responding-to-treatment/

MANY trials are ongoing with Remdesivir and other therapeutics.  We'll be seeing MANY more results of Remdesivir and other therapeutics.  If the results continue to be as positive as what we're seeing with this Univ. of Chicago trial then this could be a critical breakthrough in COVID treatment and help pave the way back to normal life sometime this summer.  

outsidethebox

April 16th, 2020 at 8:41 PM ^

Hey, Donnie makes an appearance on MGPBLOG!!! Only Trump would attempt to define the mindless handling of this pandemic by the feds as "expediting clinical trials". But yes he would.

So this retired pediatric oncology nurse mostly just hangs out on our little farm in very rural Kansas-especially now. But today I got permission (from my PNP wife) to drive the 40 miles into Wichita to fix a friends fence. Anyway, I needed to get about 25 gallons of paint to paint our house and a few more things to replace 700 sq. feet of floor. So at 0900 I got to Home Depot for fence supplies. Generally people seemed to be attempting to honor spacing and there was an "interesting" combination of mask/no mask. I did give the clerk a mini lecture regarding his no-mask look. So I got the fence fixed and went to Menards to get my stuff. It took about an hour to get the paint picked out and mixed. 

Parenthetically, I assess myself as being a fairly liberal political/social person who is also strongly "libertarian". Mainly, I respect your right to believe whatever you wish-even if you are dead wrong...as long as it does no particular harm to others. And in this regard I was not particularly cozy to or understanding of  the need for the increased pandemic restrictions in Michigan...even in the face of concern for those 15 immediate family members who are staffing the front line of this event.

What I learned today: Today after seeing the actions and behaviors of the general public I came away wondering why there are not even more restrictive measures being taken. The depth and breadth of ignorance, willful or otherwise, was astounding. Clearly the knowledge among the general population is not at a level that allows them to respect themselves let alone anyone else. Judging from what I saw today this could be a very long hard road. Ignorance does not know it exists.

BoFan

April 16th, 2020 at 9:04 PM ^

“Role in expediting clinical trials”?

Wow!  What crap are you reading. He had no role. He tried to inject himself in GMs independent expiditing of making ventilators.  He tried to inject himself in other expedited efforts that happened despite his failure to take this seriously.  He tried to take credit for just about everything he had no involvement in.  He has a 40 year record of trying to take credit for things he didn’t do while blaming other for things he did do.  He is an example of the typical corporate politician many of us have experienced first hand and for whom we know well enough to despise.
 

He now wants to pull WHO funding because they criticized him.  Please do tell us all how pulling WHO funding, at this critical time, and which all sane politicians and scientists have condemned, expedites anything?  Tell us all the benefits of pulling WHO funding to the world at this critical time?  There is only one and it is political and it only benefits Trump. 
 

The above is not political statement.  It’s just the facts. 

Sparty Doesn't Know

April 16th, 2020 at 9:49 PM ^

Uh, the issues with the WHO are way bigger than a criticism of Trump.  In fact, I would be worried if the WHO was happy with who we had in charge.

Guy is doing a bang up job keeping people's focus on the economy and freedoms.  I am glad you see Whitmer doing no wrong, but we don't need that bullshit on a national level.

wolpherine2000

April 16th, 2020 at 11:26 PM ^

You should be ashamed you are a terrible reporter let me just tell you something it's called sensationalism and very dishonest your ratings are very low and no one is even watching you and I never said that this is a very nasty thing to even say you should say congratulations but I never hear that from you people and this whole thing is very fake I would give myself a ten

BoFan

April 16th, 2020 at 10:48 PM ^

And you are a fool’s fool. Just because a fool on Twitter says WHO has a political agenda doesn’t mean it’s true. There are so many problems with that idea in the first place it should be obvious to anyone.  If you want to say WHO has a big political agenda and it’s not Trump with the agenda then you are a fool’s fool. Any historical factual analysis would show that the political agenda of Trump versus the WHO is more than 100 to 1.

But that’s always his number one method of diverting attention. Don’t look at my agenda but look at theirs. Don’t look at my finger size look at his fingers. Don’t look at my illegal foundation look at somebody else’s.  It’s a standard operating procedure from the book called the idiot’s guide to being a dictator. 

All that aside, WHO does a lot of valuable work around the globe, especially in Third World countries that have no budget. And there are two problems with cutting funding for that. One, you’re giving those countries a death sentence. Two, we can’t eliminate  a pandemic if you let it fester in half the population in the world.  That cut in funding, at this time, is not just foolish, it is stupid. 

kdog

April 16th, 2020 at 11:54 PM ^

If you don’t think the WHO tried to calm the masses when they probably should’ve been alarming them, that is fine.

Re: the third world, then let the Chinese throw $400 million at it and the US will toss in $40 million. Fuck the Chinese And their shit wet markets/virus testing. 

MrOrange

April 17th, 2020 at 11:01 AM ^

This is simply amazing! Thank you J!  This will be my biggest con ever.  So many people like this believe everything I say no matter how stupid. They can get it from Twitter or from some online troll. Nobody checks anything anymore. They bought the whole thing about my Media con. The Internet is a beautiful thing. I can get rid of the newspapers.  
 

Nobody even cares that I got rid of the guy who was supposed watch over the $2 trillion I just gave away.  This is incredible. I remember when the media started the scrutinize my fake foundation I use to pay off political favors and I just played everybody by pointing at the legit Clinton’s foundation.  We had so many fake accounts build that up it was just amazing!
 

Now I can do the same thing but even more powerfully. I get to bully foreign leaders into supporting my political agenda by withholding hundreds of millions of dollars in aid. And here is the perfect example. I’m giving away trillions of dollars to my buddies, sacking the watchdog, while I have everybody watching fake Twitter feeds about my opponent!  Hahaha!

rob f

April 16th, 2020 at 10:00 PM ^

Yes, ignorant of me to generalize chloroquine phosphate, the actual fishtank cleaning formula, as being the same thing as the lupus/malaria medication hydroxychloroquine. 

But not nearly as ignorant as the president was by promoting chloroquine as a preventive and/or cure for COVID-19 without first researching the difference between it and the fishtank cleaner (which contains a different and even more toxic formula of chloroquine phosphate) or the much safer hydroxychloroquine, which is the medicine of choice against lupus and malaria.

He promoted chloroquine several times initially, before being more specific in later news conferences in promoting hydroxychloroquine, but NOT specifically (as far as I've been able to tell) warning folks of the difference.  

Not only did Trump not do due diligence before publicly hawking his snake oil, a "cure" that killed people who simply read the word "chloroquine" on the label and injested it, he also greatly contributed to a temporary world-wide shortage of the very medicine lupus sufferers need to keep their affliction under control. 

What's more, reportedly he owns stock overseas in a company that is the biggest world producer of that very same lupus/malaria medication.  PROFIT! 

BoFan

April 17th, 2020 at 3:34 AM ^

Actually, Rob’s post can all be backed up by facts.  And what is it that you have in defense.

“Fake news” you say. That’s it?  That all you have in defense?  That is an interesting rebuttal.  I believe you learned that somewhere else and somehow think it’s a valid rebuttal. However, it is completely and utterly void of any facts. 
 

Do you think that works in class at Michigan law? No, of course not.  How about on a High School debate team? No, of course not.  Not even in a 5th grade debate.  Could you imagine that? A fifth grader in a mock debate with a rebuttal of only, “fake news”?  
 

So what do we have here? We learned it’s not a valid argument you want to use. I hope that helps.  
 

Of course, we also just verified that the “fake news” rebuttal is equivalent to a level of intelligence of less than grade-school equivalency.  Hmm

JTrain

April 17th, 2020 at 7:13 AM ^

Look. I have nothing against rob f. (or you for that matter). I’m sure he’s a great guy. But the fact that the news spends 24/7 365 spinning shit to make it look like everything that has ever gone wrong on the planet is Donald Trumps fault is ridiculous. It is, well, “fake news”.  
It is especially dumb regarding the argument of this viral pandemic. Yet the news continues to spin spin spin trying to get the general public to blame trump for any or all bad things.  People are sick of it. People are sick of shitty journalism.  Hell, it sounds like Chris Cuomo is even sick of it. 
People are sick of lifelong politicians lining their pockets With cash and looking out for themselves. People are sick of politicians that put the interests other countries ahead of our own country. 
I’ll take our guy that spars with these ass clowns on cnn and the msdnc. Who challenges the pundits that drag a guy like Kavanagh and his family through the mud yet turn a blind eye to the Joe Biden allegations.  
The news is a joke man. A joke. It’s fake.  And people don’t believe it any more.
If people thought it was real, a guy like trump never would’ve beat Hillary.  But he did. And he will win again in 2020!  

 

1VaBlue1

April 17th, 2020 at 8:12 AM ^

You probably think Fox doesn't spin anything, don't you?  And Alex Jones...  I mean, you posted a twitter thread from MAGA freak as 'news'?  Seriously?

Both sides spin news items, this much is very true.  CNN is a far left as Fox is right.  OAN is an alt-right network that favors conspiracy theories over actual news.  Twitter/FB should not be considered 'news' in any way, shape, or form.

I can post hundreds links showing facts surrounding the lies of Trump - where he actually said one thing, and then actually denies it a day later.  He does this every day, yet you believe everything he says.

I'll post this link for you to read - it's about the WHO funding decision and the actual facts about it.  Feel free to not like the WHO, but read this to learn about some legal facts.  (Disclaimer: I realize that Slate is a left-center outlet that employs some liberal POV, but it also reports facts - and this story sticks to facts pretty well, without much (if any) spin.)

And again, you can feel free to not like the WHO for reasons.  But those reasons should be based on facts rather than conspiracy theories involving hundreds of thousands of people across the world keeping secrets.  There is no 'cover up', there is only reporting what they were being told.  (The linked story is not about any 'cover up' theory.)

NeverPunt

April 16th, 2020 at 6:00 PM ^

Finding an effective treatment is a good thing no matter what side of the ridiculous arguments that I’m sure will ensue in this thread devolve into. Here’s to hoping.

carolina blue

April 16th, 2020 at 6:03 PM ^

This is good. Effective treatment is just as, if not more, important than a vaccine. There are tons of illnesses out there that have effective treatments but no vaccine. 

blue in dc

April 16th, 2020 at 6:17 PM ^

Since I think the path to using a drug already approved for other purposes to be used for a new purpose is much easier than the path for a new vaccine, this would clearly be way more important in the short term.   If a treatment has the potential to either reduce mortality or shorten hospital stays that would be a big step forward.   The anecdotes from this study seem to suggest it does both.   Will be interesting to see how the mgoblog docs weigh in on the quality of the study and other things they’ve heard.   I believe U of M is slso involved in some clinical trials for rendesivir

blue in dc

April 16th, 2020 at 6:29 PM ^

Everybody is rooting for treatments.    Just because people might have different viewpoints about the best way to get through this that doesn’t mean we we don’t all want to see it done with the least amount of damage both in terms of health and the economy.   We may disagree about how to weigh those things, but since effective treatments address both concerns, why do you and others insist on making statements like this.

PeterKlima

April 16th, 2020 at 6:49 PM ^

While most people want this to work, there is a significant portion of the population hoping for this to get worse before it gets better.  The various reasons are:

1. Sitting on the couch is the most sense of purpose they have ever had about their life.

2. Hoping to pin blame on a politician.

3. Hoping for a social upheaval that leads to a new economy, because they were doing poorly. Many of them think reopening the economy is money vs. health and essentially ignore the health impacts of a bad economy.

4. General depression.

It's sad, but as long as the risk is abstract for them, some people have hidden agendas they would never admit.