OT: Serious question re medical marijuana

Submitted by yossarians tree on

I see the usual whimsical 4/20 thread is underway, but I thought I'd take the occasion to inquire if anyone has any knowledge of medical marijuana's effectiveness specifically regarding depression. A person dear to me suffers from this affliction and is growing weary of her pharmaceutical options, especially since the answer from her doctors has seemed to be "throw something against the wall and see if it sticks."

She's never been a pothead but she has tried med. marijuana in candy form and it seems to work for anxiety (she doesn't like Xanax). It's my understanding that the modern lab-produced pot comes in a wide array of varieties that produce different results (i.e. pain control with clear head, calm mind with no physical change, etc.). Any inights you can provide would be greatly appreciated.

Yossarian

Monocle Smile

April 20th, 2017 at 2:43 PM ^

Depression can be a medical imbalance/organic damage. Depression can also be learned behavior, or a reaction to social/mental stress
I said exactly this above. This supports my case. My case is the latter, but there are loads of cases of the former, and telling these people to eschew medical treatment and just go outside and play in the sunlight is garbage.
Just look at the success of programs like AA/Narc-Anon
Yes, let's look at the "success" of programs that are dishonest about disclosing any real statistics that could be used to ascertain effectiveness. We have no idea how effective AA truly is. Someone's going to hammer me on this because either they or a loved one likely has a success story here, but that's utterly irrelevant to my point. Popularity is not indicative of success. I find the "higher power" nonsense to be psychological enslavement, and believing false things for bad reasons isn't anything I'm about to support.

gopoohgo

April 20th, 2017 at 2:55 PM ^

"I said exactly this above" : your quote: "Appealing to fiction to solve a medical issue is rather laughable.  Grow back a limb with prayer and get back to me".   

You said no such thing; you just gave a half-assed, condescending snarky response without acknowledging that depression (or many psychologic problems) is a multifactoral problem that can be genetic, organic, learned, etc.  

"We have no idea how truly effective AA is"  

Sure we do.  Older studies (1960s, 1980s) found no difference, however, the randomization did not control for cross-over.  Longitudinal studies have found an association with more active participation and abstinence.  More recent randomized trials also have shown a positive correlation between AA and abstinence.  

"I find the "higher power" nonsense to be pyschological enslavement".  

Jesus, you're a condescending piece of crap.  I'm agnostic, but I don't go out of my way to shit on other people's beliefs.

Monocle Smile

April 20th, 2017 at 3:03 PM ^

I have multiple comments in this board post. "Above" meant "upstream." Try a little harder next time. Those AA studies are loaded with problems. https://www.thefix.com/content/the-real-statistics-of-aa7301
Jesus, you're a condescending piece of crap. I'm agnostic, but I don't go out of my way to shit on other people's beliefs.
I didn't go out of my way. I saw bullshit and identified it. It's not my fault that bodies are stacked daily due to people believing false things. Children die horrible, painful deaths because their parents ignore medical treatment in favor of woo. I guess caring about reality makes someone condescending. So be it.

PapabearBlue

April 20th, 2017 at 4:30 PM ^

I never said anyone should ignore medical treatment. Also, I'd say that arguing that I said something that I didn't actually is going quite a way out of your way. Practice your reading comprehension and then reread my original post.

PapabearBlue

April 20th, 2017 at 4:30 PM ^

I never said anyone should ignore medical treatment. Also, I'd say that arguing that I said something that I didn't actually is going quite a way out of your way. Practice your reading comprehension and then reread my original post.

PapabearBlue

April 20th, 2017 at 4:33 PM ^

You just suggested that my original point of trying to find happiness within to help cure a mental ailment is not only false (thousands of years of evidence suggest its not false) but also BAD.

WTF.

Unless you're suggesting that I was trying to tell people to turn to religion. Which I wasn't and never did.

PapabearBlue

April 20th, 2017 at 4:25 PM ^

Nothing that I posted suggested that anyone turn to fiction to cure their ailments. I suggested people try to find happiness within (and that LOTS of people have suggested that because IT WORKS). It worked wonders for me and for others that I've met. Won't help everyone, then again, neither will pills.

But by all means, sit over there with your closed mind, because being close minded is NEVER dangerous.

PapabearBlue

April 20th, 2017 at 2:24 PM ^

Psylocybin and LSD have been the greatest mental health compounds that I've ever consumed but they are NOT NOT NOT NOT for everyone. If you go down this road PLEASE proceed with caution. The thing about depersonalization is that once it happens it's real hard to come back from.

CRISPed in the DIAG

April 20th, 2017 at 2:42 PM ^

Recent uses of mdma/psychedelics to treat depression use very low doses. Too lazy to link, but there is some legitimate research showing positive effects. Otherwise, I agree. Some of the worst nights of my life were spent on mind expansion while suffering depression.

Y0ST

April 20th, 2017 at 2:32 PM ^

I recently started taking CBD pills from greenmountaincbd.com. They are made from hemp and are legal in all states. I've been taking them for about two months now and my once very severe depression is all but gone. After about a week, I didn't feel any side effects from the CBD, at first there was a bit of a floating feeling. I honestly think that these pills have changed my life. I hope your friend sees the same benefit that I have.

615Wolverine

April 20th, 2017 at 2:35 PM ^

My nephew suffers from seizures he's not even 1 year old yet. I keep hearing medical marijuana can cure his seizures. Anyone know of any doctors or treatments for babies this age and medical marijuana ?

ImLawBoy

April 21st, 2017 at 11:22 AM ^

The use of marijuana extracts (primarily CBD oil, I beleve) is *extremely* promising in epilepsy research, but it's still in clinical trials.  My son was in one of those trials, and while we don't know for sure whether he was receiving the CBD vs. placebo, it was pretty obvious that he was getting the good stuff.  He was largely zoned out due to it (likely due to an interaction with another anti-seizure medication he takes), but his seizures stopped completely - from 10-30 a day down to zero.  Unfortunatley, it also spiked his liver usage (or something like that - not a doctor here), which was also due to interaction with another drug he's on.  Because it was a controlled study, we didn't have the option to take him off of the other drugs - we just had to leave the study.  Once it becomes available, though, we're getting him off the other drugs and trying out the CBD again.

 

With all that said, it's not necessarily the best treatment for all seizures.  Do you know what type of seizures your nephew is having?  If they're something called "Infantile Spasms" or "West's Syndrome", steroids are the most effective (gold standard in the US is typically ACTH) or Vigabatrin (don't be scared off by the vision side effects on that one).

 

Regardless, the best bet is to ensure that your nephew's parents are having him seen by a top notch children's hospital with a strong neurology department.  Mott isn't bad in the Midwest, but your best bets are probably Lurie Children's Hospital in Chicago or Cincinnati Children's Hospital.  Push the doctors hard, and don't be afraid to seek second opinions if treatment is not working.  Controlling epilepsy is an art as much as it is a science, and sometimes a different doctor can make all the difference.  A good doctor shouldn't be insulted or threated by news that parents want to seek a second opinion.

Swavo

April 20th, 2017 at 2:41 PM ^

 Just to let you know; You can't get your MMM card for depression. I suffer from chronic pain from Car accidents and Snowboarding when I was younger but the real reason I got it was for depression. I just used the chronic pain schtick as my excuse to get it for my depression. Make up something in regards to chroninc pain if you don't have an excuse because the PTSD / depression schtick won't work.

My wife and I were going through a rough patch. I went therapy but I needed additional help. My doctor prescribed Lipitor. It wasn't giving me the disired effect after upping the dosage after multiple visits plus there were side effects. Marijuana helped me in the past through some tough spots and I decided to get legal. 

If you're looking to combant depression via cannabis many Sativa (day time) strains help. They usually make you feel content, energetic, happy, uplifted, euphoric, relaxed, and ready to take on the day. I wake up in the morning to Sativa strains. You do have to be a little careful though as Sativa strains can also give you a undesired feeling of anxiousness and paranoia if you medicate with too much Sativa. High CBD Strains help combant those feelings when they occur. 

Indica (Night time) Strains can also help with depression. Indica effects the body more than where Sativas is more in the head. Indica makes you relaxed, sleepy, happy, and hungry. These strains are great before going to sleep or if you looking to chill. You can feel anxious and paranoid too if you medicate with too much Indica, So having some form of CBD help level you out. CBD is also great for pain. 

Leafly is a great app that breakdowns Indica / Hybird / Sativa / CBD strains if you're looking to treat certain ailments. 

Weedmaps is also a great app to find doctors to get legal, dispensaries to browse their menus, delivery services, and also deals.

I hope this was helpful. 

DenardPeppers

April 20th, 2017 at 2:47 PM ^

I can comment that pot can be used to increase anxiety in people and also cause some sort of paranoia.  There are different strands thought that are used for different things.  Pot high in CBDs are made mainly for pain.  There are also kinds that make you high as hell,  Weed has many postive uses and should imo be legal.   That being said the chemical makeup does have similar qualities to that of LSD.  So who knows.   They have also used Ketamine for depression and foound that works great for people and instantly.  I dont have the study link off hand but pretty sure the people who had these treatments had major depressive disorders and were resistant to the antidepressants out there.   

yossarians tree

April 20th, 2017 at 2:52 PM ^

Thanks for all the suggestions. I believe at its heart depression is a chemical imbalance in the brain, but it sends a person on a spiral downward that consumes every aspect of a life and is hard to stop. Bad feelings beget bad feelings, beget listlessness, poor diet, and lack of excercise, etc. She just gets buried under it. Depression is a tricky motherfucker, and it really just consumes a person's soul--literally like a possession. I think she should try a more naturopathic approach--and I consider marijuana to be a part of this approach, provided it does not in itself become an addiction. I think you have to find a way to chemically hold it at bay and then stay on top of it through healthy living. Once it gets its hooks into a person, well, it is understandable how thoughts of suicide become louder and louder.

DenardPeppers

April 20th, 2017 at 7:55 PM ^

Depression is hereditary also besides having some kind of lack of chemicals or an imbalance. My grandpa was depressed and had anxiety problems and he ended up taking his life and now my uncle has almost the same type but he is on meds now but has never held a real job. I started developing depression also with anxiety and it is a vicious cycle. I have been at a point where nothing would interest me and I would just cry for no reason. It can get so bad u can't function or live a normal life. I think we need to look at mental health problems different. People often are looked down upon for even admitting they have a problem and that is why some people don't get help because they feel ashamed or embrassed. All these killings that happen are usually because that person has some kind of mental health problem and didn't or couldn't get help. My heart goes out to all the people who suffer through some kind of mental health problem because life is hard enough and to add this to it makes it that much harder.

BursleyBaitsBus

April 21st, 2017 at 8:28 AM ^

Anxiety Depression is an interesting case study bc you have to figure out whether the depression is causing the anxiety or vice versa. CBT is a good way to figure out which one causes what bc if you don't pin point the true cause, you won't ever feel content. I would recommend CBT in conjunction with anything else.

bluepow

April 20th, 2017 at 3:03 PM ^

Omega 3's (1000mg to 2000mg per day of the EPA variant in particular) are worth trying.  They work best when combined with a healthy dose of fruits, veggies, and exercise...but duh of course.  

Personally I think weed legalization out here in Colorado has improved both lives and economy but I am glad other states are coming on board because also feel it is a case of can have too much of a good thing.

reshp1

April 20th, 2017 at 3:00 PM ^

Not sure about MMJ for depression, but there has been a lot of recent news about success treating depression with ketamine. It's pretty experimental at this stage, so it might be an issue getting a doctor to try it, but worth asking about.

DenardPeppers

April 20th, 2017 at 7:53 PM ^

The studies about Ketamine I read I think we're still in the study phase but it was a good read cause the depression went away almost immediately after treatment and lasted for 3 months or more a d then you would go back and do the same thing but the depression would go away even longer. Hard to believe Special K can do this.

Sinsemillaplease

April 20th, 2017 at 3:10 PM ^

Lexapro almost led me to take it.... 10 years later and medical marijuana still combats the existential dread and bouts of major depressive disorder better than anything else I have tried. Don't let any of the many many doubters that think you just want to get high dissuade you.... those people don't actually care whether you live or die.

mackbru

April 20th, 2017 at 3:10 PM ^

As someone with some experience with both, I'd tell you that weed can help occasionally -- but chronic use can come with its own pitfalls. Weed tends to be de-motivating and spur fatigue and general societal withdrawal. If she's gonna use it, she should choose her spots. Sativa tends to be better for depression and indica for anxiety. But tread gently. 

JLo

April 20th, 2017 at 3:20 PM ^

I've never tried medical marijuana as a treatment, so I can't comment on its effectiveness.  But if your wife is looking for treatment options aside from pharma, I highly recommend meditation.  I took a vipassana meditation class a few years ago, and it's developed into a regular practice.  I've had some breakthroughs while sitting in meditation that have totally changed how I relate to my thoughts and emotions.  It got me out of some really self-destructive cycles.

PapabearBlue

April 20th, 2017 at 4:38 PM ^

LMAO, you are the same guy that told me religion and philosophy were fiction that shouldn't be spread and here you are spreading practices about finding happiness within and those practices were rooted in religion and philosophy. Nice job dude. Better watch out, you see your own advice as dangerous.

Monocle Smile

April 20th, 2017 at 5:39 PM ^

Try reading INTO what I'm saying rather than just one word after another.

As I said in my very first comment that you jokers apparently ignored, depression can be environmental or it can be due to a physiologial chemical imbalance. 

Environmentally triggered depression can definitely be mitigated with meditation and mindfulness, which are both what you get when you take some Eastern religious practices and strip out all the woo-woo. I see this whole "critical thinking" thing is hard.

Chemical imbalances can't be fixed by religion or "thinking better" or "lifestyle choices" or any of that. You basically took a shit on the entire idea of pharmaceutical treatment upthread, which is something I don't wish to leave unchallenged.

I've been consistently making this distinction and yet somehow you're still lost.

B-Nut-GoBlue

April 20th, 2017 at 6:41 PM ^

I think you went at him claming he was bringing religion into the conversation when he really meant exactly what you just posted above.  That's how I'm sort of seeing this play out.

 

meditation/mindfulness, etc. = finding yourself within (what he said above)

PapabearBlue

April 20th, 2017 at 6:48 PM ^

In your very first post your only connection between the chemical imbalance and any other causation was, "tons of depression cases are due to a chemical imbalance". So, lets not overexaggerate. On top of that, nowhere did I say you didn't say or believe those things.

Nowhere did I say anything about the pharmaceutical industry except, "pills wont fix everything". That is literally all that I said about it.

In your first post you said that I was spreading dangerous nonsense. Your quote was, "Tons of depression cases are due to a chemical imbalance. No amount of navel-gazing is going to fix that. You are spreading dangerous nonsense."

Ok, so, We've established that not once have I said anything about the pharmaceutical industry. I have also never told anyone not to seek therapy or medical treatment. What I did suggest was, "get enough sleep, exercise/physical activity, eat clean/healthy, meditation, and something to make you grow personally". I also suggested that people with depression try to find happiness within.

I then said that many religions AND philosophies say that you should do the same thing, I said this because lots and lots of people have found this effective enough of a tool for treating many mental ailments that it has become a popularly supported method. There are easily accesable factual studies showing this to be true. Nowhere did I say anyone should turn to religion, I am NOT religious nor pro religion.

I'm VERY aware that many people practice meditation as a method of peace and that this practice has been stripped of it's original reliigous connection. I DID however point out the irony that you found my post "DANGEROUS" yet later on suggested that people do the VERY SAME THING in using meditation to treat depression. Which, ya know, meditation is a tool for internal peace and happiness.

For being so wrong you have been so condescending. My thoughts aren't dangerous, you're just an idiot who needs to make shit up to support your argument or give yourself a platform for whatever cause you need to champion. Fuck off.

BursleyBaitsBus

April 21st, 2017 at 8:32 AM ^

Quiet down you two. Depression can be 2 fold. Either chemical imbalance or attitude driven. One can delve into the other. It's imperative you figure out which one you have if you're feeling depressed or else medications or internal peace of mind will not help.

BallsoHarb

April 20th, 2017 at 3:20 PM ^

A lot of factors go in to this decision, but I do not advocate the use of marijuana for a younger person. Complications can arise that can be quite debilitating, and marijuana can in fact make depression worse with long term use and there is a suspicion that it can up regulate the genes linked to schizophrenia. If nothing really works, it may be an option, but meditation, therapy pets, and other non pharmaceutical options do exist, it is a kind of "let's throw something at wall" approach.

BallsoHarb

April 20th, 2017 at 6:30 PM ^

They do not. I have a friend who was diagnosed with schizophrenia, and there is a possibility that the onset of his disease was in part due to his marijuana use. He also tends to have more episodes of psychosis when he uses marijuana. The main reason a link between the two is not firmly established (and why meds don't work for some people) is that it is difficult to measure hormone levels in the brain, so cause and effect relationships can't be measured objectively at this time.

DenardPeppers

April 20th, 2017 at 8:01 PM ^

What you are talking about is seasonal depression and yes D3 supps will help along with an occasional tanning bed trip or the light therapy units they make. Then you have some depressions that winning the lotto or even sleeping with Katie Upton won't cure it. These type need major therapy and or some type of meds to get their brain right. Then there are Some who just don't respond to anything and that's where the Special K experiments and other out of the box stuff is being studied.

Elno Lewis

April 20th, 2017 at 4:08 PM ^

good old fashioned physical exertion?  mountain biking?  running?  swimming?  I do know a little about this (professionally) and my first suggestion was always some sort of physical exertion.  You'd be surprised how often this worked.  Even some people who were already on meds got off them once they started working out hard.

A good hard workout releases natural chemicals in the body that can alleviate anxiety, depression and a few other maladies.

Poster above was correct with the sativa suggestion.  

 

 

 

Erik_in_Dayton

April 20th, 2017 at 4:29 PM ^

I'm well aware that excercising when you're depressed is easier said than done, but it's a great help in my experience.  I'd choose a very easy goal if she has trouble getting started, like walking .5 miles a day.  She should set goals that she'll almost surely meet in order to minimize the chance of becoming discouraged.  Not everyone has to be a marathon runner. 

I should add that I'm not a doctor and that I don't mean to suggest that excercise is all that is needed for the OP's friend or anyone else.  But as someone who's struggled with depression, I wish I'd started working out sooner than I did.

Opinion25

April 20th, 2017 at 5:47 PM ^

Well controlled trails are generally need to determine if a treatment helps, hurts or does nothing. Unfortunately, we have virtually no such trials for MJ for anything other than it decreases cognative ability acutely. Trials of other proposed "natural" treatments have almost all been negative or shown net harm, which demonstrates that anecdotes are a poor substitute for good science.

PapabearBlue

April 20th, 2017 at 10:00 PM ^

I'm not disagreeing with a lot of this, but what other types of "natural" cures are you lumping MJ in with. If it's anything like I imagine then MJ is nothing like those.

pbmd

April 20th, 2017 at 6:36 PM ^

I do not claim any expertise regarding this subject.

Do not expect any solid, scientific evidence regarding this drug. Conducting research in this area is very problematic.
Marijuana makes you high - many people like that feeling.
What those effects are over a large population is poorly understood.
Do not expect many "mainstream" medical doctors will prescribe it recommend marijuana as a therapy.

slimj091

April 20th, 2017 at 6:37 PM ^

Honestly it's different for everyone. In my case I prefer a full Sativa for depression. It keeps my mind sharp,elevates my mood, and at the same time keeps me active so I don't have time to dwell pas traumatic events.

But some people with depression different than mine might not care for that kind of effect. Her best bet would be to consult a cannabis friendly doctor to see what would be best for her, or even if it would be best for her at all.