I left a fair amount of Brian's analysis out of this MPP because it didn't translate particularly well to video. If you haven't read Brian's original PP, go do it now. If you have, go do it again.
Setup: Michigan has it first-and-ten on their own 38 on their first drive of the game. They come out in a 'power' shotgun (a 12-gauge, if you will) with two backs and a TE, and will run an iso to the right utilizing combo blocks on the NT and a lead blocker (Hopkins).
Wha'hoppon: Schofield and Molk plant the NT like he's a burlap-wrapped sapling. Omameh and Huyge single-block their men halfway to the bench, Denard freezes the backside DE with his ever-present run threat, and Hopkins roars into the hole. He gets his helmet across the LB and blasts him out of the hole, collecting a safety who really sucks at geometry in the process. This turns out to be key to the play, since it both completely opens the hole and eliminates the man-advantage Minnesota had by walking an extra safety down into the box. Toussaint flies through the hole untouched until he gets well into the secondary, and breaks an ankle-tackle on his way to a 35-yard gain.
Full YouTube link is at http://www.youtube.com/watch?v=5U0Wh_TNn5E