"The University of Illinois is also in turmoil. The university sports an Interim Chancellor, an Interim Athletic Director, and an Interim Football Coach; the game will be played at Soldier Field, making this an Illini Interim Home Game."
The article at the link makes 4 points about the hazards of decision-making in football. The study used data from the NFL, but it's definitely relevant to the college game.
In particular, it seems relevant discussion on MGoBlog about:
1. going for it on 4th down (do it!)
2. whether it helps the team to fire the coach (not really, but there needs to be a GERG exception, IMO)
3. winning with someone else's talent (WOO! go Brady, Borges, and Mattison)